PD-1100 Pulsatile Pump System

BDC Laboratories’ PD-1100 pulsatile pump system provides a highly versatile, reliable and repeatable pulsatile flow source for accurately simulating physiological hemodynamics in vitro, in both an industry and academic environment. The numerous applications of the PD-1100 pulsatile pump include: ex-vivo beating heart models, simulated use testing platforms, pulse duplicators, particle image velocimetry (PIV) systems, bioreactors and physician training platforms.

The PD-1100 pulsatile pump’s accompanying software, Statys® PD, provides an exceptionally effective, operator-based control and monitoring environment that enables full engagement with all the system’s capabilities. Integrated in the software is comprehensive driving waveform definition, which is interfaced either through an adjustable built-in controller, or an integrated custom waveform creator tool. Too numerous to list, the extensive hardware and software accessories facilitate tailoring each PD-1100 pump system for its application, yielding unmatched performance in all pulsatile flow systems.

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Specifications & Benefits

• Extensive list of accessories available to tailor the pulsatile pump system to any cardiovascular technology, test platform or simulated use pulsatile flow network for structural heart & endovascular applications.
• Closed-loop pump control provides a superior beat-to-beat repeatability during operation.
• Frequency: 10 to 240 bpm
• Stroke Volume: 
  • 0 to 50 ml (small piston)
  • 0 to 290 ml (standard piston)
  • 0 to 450 ml (large piston)
• Flow rate:
  • 0 to 2 L/min (small piston)
  • 0 to 10 L/min (standard piston)
  • 0 to 25 L/min (large piston)
• Driving Waveform: Sinusoidal, arbitrary
• Synchronization/Triggering: TTL and analog
• Self Priming: Yes, with pulsatile pump head
• Regulatory Compliance: Complies with all applicable European Union directives and standards for safety and EMC. CE Marked; RoHS Compliant.

Statys PD Software

• Sinusoidal or arbitrary waveform driver excitation to accurately simulate clinical performance
• Hardware-based deterministic timing for exceptional beat-to-beat repeatability and reproducibility performance
• Integrated data collection for real-time reviewing of test parameters
• Optional data collection and analysis tool-kits for a variety of applications, including heart valve prostheses and valve repair devices
• All measurement signals can be saved in high-fidelity for post-test analysis
• User-focused software environment to facilitate ease of system operation
• Highly versatile and adaptable for any general cardiovascular, stent, stent graft, heart valve or valve repair application

Accessories

• Pulsatile Pump Head:
  The Pulsatile Pump Head enables the PD-1100 to function as a positive displacement pulsatile pump. Featuring a barbed inflow and outflow port, both with one-way valves, and self-priming performance, the Pulsatile Pump Head allows convenient inclusion into a fluid loop.
• Oscillating Flow Pump Head:
  The Oscillating Flow Pump Head provides a means for the PD-1100 to function as a oscillating flow source. With a single, large diameter inflow/outflow connection, the Oscillating Flow Pump Head provides the appropriate interface when used with ex-vivo beating heart models.
• Hemodynamic Flow Conditioner:
  The Hemodynamic Flow Conditioner is an all-in-one addition to the PD-1100 that emulates the vascular bed. The Conditioner has integrated directional valves, a fluid reservoir, a compliance chamber, a resistance element and an optional heater.
• Heart Function Emulator, HFE:
  The Heart Function Emulator is connected to the pulsatile flow pump and serves to emulate the contractile and resistive conditions of the heart, resulting in a more clinically relevant flow and pressure source for cardiac applications. The HFE consists of an impedance element and compliance chambers. The compliance volumes can be adjusted to tune the shape of the flow waveforms.
• Fluid Isolation Module:
  The Fluid Isolation Module serves to isolate the test solution from the pump fluid. This allows the user to run particles in the test solution without damaging the PD-1100 drive seals, as well as maintain the sterility of the test solution without needing to treat the PD-1100 driver assembly.
• Diastolic Pressure Control:
  The Diastolic Pressure Control replaces the standard Pulsatile Pump Head outflow assembly with a tunable element that serves to control a cardiac flow network’s diastolic filling pressure, resulting in a more clinically relevant pressure environment for prosthetic valve applications.
• High-Speed Video:
  Integration of up to three (3) high-speed cameras transforms the PD-1100 pulsatile pump system into a comprehensive research tool. The acquired video is synchronized with the pressure and flow waveforms and can replayed with the integrated video player at a user-defined frame rate to fully appreciate the dynamic response of the target. Additional integrated tools further provide a means to make dimensional measurements from the video.
• Fluid Heating Reservoir:
  The Heating Reservoir allows the user to control the temperature of the system fluid and provides a convenient system filling location. The Heating Reservoir features a heating element, inflow and outflow ports, a drain valve, temperature probe and safety switch.
• Acrylic Compliance Chamber:
  The Compliance Chamber acts as a dampening element that allows the operator to tune the pressure pulse. The Chamber mimics the elasticity of the arteries in the vascular bed.
• Additional Pressure Transducers:
  The PD-1100 pulsatile pump system is sold standard with one pressure transducer. The Statys PD software and data acquisition hardware provides a means to add up to three (3) additional transducers to facilitate comprehensive pressure measurement in any mock circulation loop.
• TTL System Trigger:
  The TTL System Trigger provides an output TTL signal that synchronizes the PD-1100 pump with secondary systems, such as particle image velocimetry (PIV) systems.
• Small Piston:
  The Small Piston optimizes the PD-1100 for low flow applications up to 2 L/min.
• Lage Piston:
  The Large Piston optimizes the PD-1100 for high flow applications up to 25 L/min.
• Hydrodynamic Testing Module:
  The Statys PD Hydrodynamic Testing Module enables the user to perform real time analysis of valve functional performance based on the ISO 5840 requirements. The data is segregated into individual pulses and then analyzed based upon cursors indicating key events in the cardiac cycle.
• Autonomous Run Module:
  The Statys PD Autonomous Run Module allows the user to conduct extended duration tests in a controlled, monitored and documented environment when the operator is not attending the running system (e.g. the PD-1100 system will continue to run throughout the night). The package includes: historical plotting, alarm safety features and statistical data logging. The down sampling data logger option is also included with this package.
• Multi-Mode Waveform Controller:
  The Statys PD Multi-Mode Waveform Controller allows the user to easily switch between up to three user pre-defined run conditions (e.g., normal to an atrial fibrillation mode). When the operating mode is changed, the pump automatically changes from the current run condition to immediately start another predefined run condition.
• ECG Signal Module:
  When running the PD-1100 in conjunction with clinical equipment designed to operate with an ECG signal, the Statys PD ECG Signal Module generates an actual ECG waveform to interface with the clinical equipment.
• Downsampling Data Logger:
  The Statys PD Downsampling Data Logger allows the user to reduce the sampling rate and create a more manageable data file. This is advantageous when recording data at a high rate (e.g., 1 kHz) is not desired or when an experiment is carried out over a long period.